HomeDeal TypeBuy OutNetherlands: NLC records two exits - Serda Therapeutics and Sanmirna

Netherlands: NLC records two exits – Serda Therapeutics and Sanmirna

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NLC Health Ventures, Netherlands-based early-stage healthtech venture investor and operator, has sold its shareholding in Serda Therapeutics  in a transaction paid fully in cash. Terms were not disclosed.

With its joint venture partner taking a majority position, Serda gains the focused backing of a global medical technology group as it advances the technology. Founded in 2020, Serda – a joint venture between Smith & Nephew and NLC – is a clinical-stage biopharmaceutical company developing a prescription product for fast and effective wound debridement. Its lead product, SN514, uses a proprietary proteolytic enzyme to selectively remove necrotic tissue and eschar from burn wounds and chronic ulcers.

“As we enter this next phase, we are committed to advance SN514 through later-stage clinical development,” said Gabor Heltovics, CEO, Serda Therapeutics.

In 2024, Serda raised €2m in a funding round led by NLC’s Health Impact Fund. 

‍“Serda reflects what our model is built to do: take an early-stage invention and develop it into a clinical-stage company addressing a real patient need,” said Ian Metcalfe, partner, NLC Health Ventures‍

‍This was the second exit for NLC Health Ventures within a three-week period.

In June, it sold its shareholding in US-headquartered Sanmirna, a clinical-stage biopharmaceutical company bringing curative therapies to patients with Acute Myeloid Leukemia (AML), to London-listed Thalia Therapeutics.

Thalia Therapeutics is acquiring the entire issued share capital of Sanmirna for an initial consideration of £3.75m (US$5m) in equity, with additional deferred milestone payments in equity and cash of up to £13m contingent on clinical, regulatory, and commercial milestones being met. NLC Health Ventures, the largest shareholder in Sanmirna, will receive, as part of the transaction, direct equity ownership in a listed biotech company.

By joining Thalia, Sanmirna expects to gain the platform, resources and listed infrastructure to accelerate its lead asset, MiRisten, clinical programme with Phase I results expected in the first half of 2027. MiRisten, a microRNA therapeutic candidate that selectively inhibits miRNA-126 – a gene believed to play a critical oncogenic role in (AML).

NLC founded Sanmirna to bring a promising scientific discovery from City of Hope, Los Angeles, into the clinic.

NLC has over 70 ventures in Europe and the US, with a portfolio spanning various health technologies from biotechnology, to cardiovascular solutions and orthopaedics inventions.

Nick Herbert
Nick Herbert
Nick Herbert has over 30 years’ experience in the financial markets, as both a practitioner and journalist. He started work as an investment banker in London, before joining International Financing Review (IFR) to report on debt capital markets and derivatives. He moved to Singapore in 2000 to manage IFR’s financial markets editorial team throughout Asia, before returning to London in 2009 to take up the position of Publisher for Reuters Capital Markets Publications. For the last five years he has been covering global capital markets, ESG finance and healthcare markets on a freelance basis.
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